Publications

2019

Pan-viral serology implicates enteroviruses in acute flaccid myelitis. Nature Medicine. 2019.

Kelch-like Protein 11 Antibodies in Seminoma-Associated Paraneoplastic Encephalitis. New Engl J Med. 2019. (Accompanying Editorial).

Exploratory Proteomic Analysis Implicates the Alternative Complement Cascade in Primary CNS Vasculitis. Neurology. 2019.

Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis. New Engl J Med. 2019.

Metagenomic next-generation sequencing of samples from pediatric febrile illness in Tororo, Uganda. PLoS ONE. 2019.

Unbiased metagenomic sequencing for pediatric meningitis in Bangladesh reveals neuroinvasive Chikungunya virus outbreak and other unrealized pathogens. preprint on bioRXiv (3/15/19); doi: https://doi.org/10.1101/579532

Exploration of Anti-Yo and Anti-Hu paraneoplastic neurological disorders by PhIP-Seq reveals a highly restricted pattern of antibody epitopes. preprint on bioRXiv (12/20/18); doi: https://doi.org/10.1101/502187

Longitudinally persistent cerebrospinal fluid B-cells can resist treatment in multiple sclerosis. JCI Insight. 2019.

2018

Clinicopathology Conference: 41 year old woman with chronic relapsing meningitis. Annals of Neurology. 2018.

Pediatric brainstem encephalitis outbreak investigation with metagenomic next-generation sequencing. preprint on bioRXiv (9/12/18); doi: https://doi.org/10.1101/414979

Whole-Genome mRNA Gene Expression Differs Between Patients With and Without Delirium. J Geriatr Psychiatry Neurol. 2018.

Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing. JAMA Neurol. 2018 (Accompanying Editorial)

Fatal Powassan Encephalitis (Deer Tick Virus, Lineage II) in a Patient With Fever and Orchitis Receiving Rituximab. JAMA Neurol. 2018

Stroke incidence is highest in women and non-Hispanic Blacks living with HIV in the ALLRT cohort. AIDS. 2018

2017 and earlier

Clonal relationships of CSF B cells in treatment-naive multiple sclerosis patients. J Clin Invest Insight. 2017

A Novel Cause of Chronic Viral Meningoencephalitis: Cache Valley Virus. Ann Neurol. 2017

MRI Atlas-Based Measurement of Spinal Cord Injury Predicts Outcome in Acute Flaccid Myelitis. AJNR Am J Neuroradiol. 2016

Neurologic Complications of Common Variable Immunodeficiency. J Clin Immunol. 2016

Emerging Diagnostic and Therapeutic Tools for Central Nervous System Infections. JAMA Neurol. 2016

Acute West Nile virus meningoencephalitis diagnosed via metagenomic deep sequencing of cerebrospinal fluid in a renal transplant patient. Am J Transplant. 2016

Illuminating uveitis: metagenomic deep sequencing identifies common and rare pathogens. Genome Med. 2016

Multiplexed Metagenomic Deep Sequencing To Analyze the Composition of High-Priority Pathogen Reagents. mSystems. 2016

Next-generation sequencing of tissue: A logical extension. Neurol Neuroimmunol Neuroinflamm. 2016

Depletion of Abundant Sequences by Hybridization (DASH): using Cas9 to remove unwanted high-abundance species in sequencing libraries and molecular counting applications. Genome Biol. 2016

Diagnosing Balamuthia mandrillaris Encephalitis With Metagenomic Deep Sequencing. Ann Neurol. 2015

Actionable diagnosis of neuroleptospirosis by next-generation sequencing. New Engl J Med. 2014